Electromagnetic Navigation Bronchoscopy guided indocyanine green injection for localization of pulmonary nodules–system review and meta-analysis
X. Maoa (Dr), H. Hua (Dr), E. Chen*a (Prof)
a Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, CHINA
Background: Precious location for peripheral pulmonary lesions (PPLs) is crucial for surgery operation. Injection indocyanine green (ICG) with the guidance of electromagnetic navigation bronchoscope (ENB) is newly developed method in locating PPLs. But the operation success rate various in different centers. Thus we conduced this meta-analysis to evaluate the pooled operation success rate of this new method.
Method: We used the key words of “ICG” or “indocyanine green” AND “electromagnetic navigation” AND “lung” or “pulmonary”. Publications before 31st Mach, 2022 are searched. The references of selected studies were also reviewed. The detailed data were extracted, respectively. And the operation success rate was pooled with the STATA 22.0.
Result: Finally, four studies, including 309 PPLs, are enrolled in meta-analysis. The operation success rate various from 86.0% to 100.0%, and the pooled operation success rate is 93.2% (95% confidence interval: 86.0 - 98.2%). No complications reported.
Conclusion: Injection ICG with the guidance of electromagnetic navigation bronchoscope (ENB) is a excellent method in locating PPLs.
Disclosure of funding source(s):
This work was support by Key R&D Program of Zhejiang (2022C03086).