V. Dimitrica (Mr), M. Marc Malovrha (Dr), K. Adamica (Mrs), A. Rozman*a (Dr), T. Nemanica (Mrs)

a University Clinic Golnik, Golnik, SLOVENIA

* vladimir.dimitric@klinika-golnik.si

Background: The correct diagnosis of the interstital lung disease can be challenging and requires multidisciplinary team approach. Integral part of the diagnostic process is the histological examination of the lung tissue sample which can be obtained using criobiopsy technique.

Methods: In our study, we retrospectively observed 94 patients in the years from 2016 to 2019. All patients had previously been assed by a multidisciplinary medical consultation team that indicated bronchoscopic cryobiopsy. After receiving the histological diagnosis, the patients were presented anew, with the aim of determining the final diagnosis.

Results: 94 patients were included in the study, thereof 57 men (61%) and 37 women (39%), with the average age of 66 years (36-80). Following the assessment to the multidisciplinary medical consultation team, a final diagnosis was determined for 90 patients, of which 4 required a VATS biopsy. In 10 patients (10.6%) pneumothorax occurred; 6 required pleural drainage, 4 only observation. There were 6 (6.4%) major, 27 (28.7%) moderate and 61 (64.9%) minor incidences of bleeding. One patient had paroxysmal atrial fibrillation.

Conclusion: Bronchoscopic cryobiopsy is an accessible and, in experienced hands, safe diagnostic method, with which we can acquire suitable histological material needed for the final diagnosis of interstitial lung disease. According to our experiences, it represents a good alternative to open surgical lung biopsy.

Disclosure of funding source(s): none